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University of New Mexico Center for Molecular Discovery


Assays Published in PubChem (as of March 2008)

# AID Title Application Method Tested Active Status
1 362 Formylpeptide Receptor Ligand Binding Assay NA Screening 4282 61 Completed
2 440 Primary HTS Assay for Formylpeptide Receptor (FPR) Ligands and Primary HTS Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands 1R03MH076381-01 Screening 24304 181 Completed
3 441 Primary HTS Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Primary HTS Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands 1R03MH076381-01 Screening 24304 72 Completed
4 519 Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands 1R03MH076381-01 Confirmatory 272 24 Completed
5 520 Dose Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Ligands and Dose Response Counter-Screen Assay for Formylpeptide Receptor (FPR) Ligands 1R03MH076381-01 Confirmatory 272 6 Completed
6 698 Secondary Calcium Response Assay for Formylpeptide Receptor-Like-1 (FPRL1) Antagonists 1R03MH076381-01 Screening 7 3 Completed
7 699 Secondary Calcium Response Assay for Formylpeptide Receptor (FPR) Antagonists 1R03MH076381-01 Screening 34 16 Completed
8 722 Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Primary HTS Assay 1R03MH076381-01 Screening 1276 38 Completed
9 723 Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1) 1R03MH076381-01 Confirmatory 58 0 Completed
10 724 Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay 1R03MH076381-01 Confirmatory 58 15 Completed
11 725 Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Primary HTS Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1) 1R03MH076381-01 Screening 1276 1 Completed
12 762 Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : FPR Dose Response Counterscreen Assay 1R03MH076381-01 Confirmatory 15 0 Completed
13 763 Formylpeptide Receptor-Like-1 (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : FPR Primary HTS Assay Counterscreen 1R03MH076381-01 Screening 170 1 Completed
14 765 Formylpeptide Receptor-Like-1 (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Primary HTS Assay 1R03MH076381-01 Screening 170 3 Completed
15 766 Formylpeptide Receptor (FPRL1) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay 1R03MH076381-01 Confirmatory 15 5 Completed
16 805 Assay for Formylpeptide Receptor Family Ligands: Target Formylpeptide Receptor 1R03MH076381-01 Summary 15 15 Completed
17 863 Formylpeptide Receptor (FPR) Structure Activity Relationship (SAR) Analysis: Secondary Calcium Response Assay for Antagonists 1R03MH076381-01 Other 15 9 Completed
18 1061 Formylpeptide Receptor-Like-1(FPRL1) Structure Activity Relationship (SAR) Analysis: Secondary Calcium Response Assay for Antagonists 1R03MH076381-01 Screening 6 3 Completed
19 1202 Assay for Formylpeptide Receptor Family Ligands: Target Formylpeptide Receptor-Like-1 1R03MH076381-01 Summary 6 6 Completed
20 757 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype 1RO3MH081231-01 Screening 194655 521 Completed
21 758 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype 1RO3MH081231-01 Screening 194659 107 Completed
22 759 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype 1RO3MH081231-01 Screening 194653 267 Completed
23 760 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype 1RO3MH081231-01 Screening 194656 365 Completed
24 761 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype 1RO3MH081231-01 Screening 194656 398 Completed
25 764 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant 1RO3MH081231-01 Screening 194653 219 Completed
26 751 Disassembly of the 26S Proteasome (ATP Hydrolysis-dependent) 1X01MH077613-01 Screening 23718 39 Completed
27 1062 Disassembly of the 26S Proteasome (ATP Hydrolysis-dependent): Dose Response Assay 1X01MH077613-01 Confirmatory 21 2 Completed
28 1207 Flow Cytometric GFP Protein Degradation Assay: Secondary Assay for disassembly of the 26S Proteasome 1X01MH077613-01 Screening 3 1 Completed
29 1210 Estrogen Receptor (beta) binding: Primary Screen 1X01MH077627-01 Screening 822 58 Completed
30 1211 Estrogen Receptor (alpha) binding: Primary Screen 1X01MH077627-01 Screening 822 71 Completed
31 1212 GPR 30 Binding: Primary Screen 1X01MH077627-01 Screening 151 15 Completed
32 1213 CALCIUM_SIGNALING_VIA_GPR30: Primary Screen 1X01MH077627-01 Screening 99 22 Completed
33 1218 Functional assay for estrogen-mediated translocation of PIP3: Secondary Assay for Estrogen receptor beta 1X01MH077627-01 Screening 12 3 Completed
34 1219 Functional assay to assess estrogen-mediated translocation of PIP3: Secondary Assay for GPR30 estrogen receptor 1X01MH077627-01 Screening 12 3 Completed
35 1221 Estrogen Receptor (beta) binding: Dose Response of Primary Screen Assay 1X01MH077627-01 Confirmatory 63 14 Completed
36 1223 Estrogen Receptor (alpha) binding: Dose Response of Primary Screen Assay 1X01MH077627-01 Confirmatory 63 17 Completed
37 1224 GPR 30 Binding: Dose Response 1X01MH077627-01 Confirmatory 10 3 Completed
38 1226 Functional assay for estrogen-mediated translocation of PIP3: Secondary Assay for Estrogen receptor alpha 1X01MH077627-01 Screening 12 4 Completed
39 528 Allosteric Agonists for the VLA-4 Integrin 1X01MH077638-01 Screening 23786 2 Completed
40 529 Allosteric Antagonists for the VLA-4 Integrin 1X01MH077638-01 Screening 23786 48 Completed
41 576 Auto-fluorescence of compounds effecting screening of VLA-4 Integrin 1X01MH077638-01 Other 23785 146 Completed
42 702 Dose-Response of Allosteric Antagonists for the VLA-4 Integrin 1X01MH077638-01 Confirmatory 62 34 Completed
43 703 Dose-Response of Allosteric Agonists for the VLA-4 Integrin 1X01MH077638-01 Confirmatory 5 0 Completed
44 795 MLSCN Assay for Activators of Prostate Cell Differentiation 1X01MH078937-01 Screening 23718 134 Completed
45 1069 MLSCN Assay for Activators of Prostate Cell Differentiation: Single point confirmation of side scatter shift 1X01MH078937-01 Screening 430 50 Completed
46 1076 MLSCN Assay for Activators of Prostate Cell Differentiation: Single point confirmation of potential cell killers 1X01MH078937-01 Other 430 29 Completed
47 1196 MLSCN Assay for Activators of Prostate Cell Differentiation: Secondary Dose Response Assay 1X01MH078937-01 Confirmatory 95 35 Completed
48 1197 MLSCN Assay for Activators of Prostate Cell Differentiation: Primary Screen Dose Response of Potential Cell Killers 1X01MH078937-01 Confirmatory 95 19 Completed
49 1198 MLSCN Assay for Activators of Prostate Cell Differentiation: Primary Dose Response Assay 1X01MH078937-01 Confirmatory 95 29 Completed
50 1200 MLSCN Assay for Activators of Prostate Cell Differentiation: Counter Screen Dose Response of Potential Cell Killers 1X01MH078937-01 Confirmatory 95 37 Completed
51 527 Primary HTS Assay for Inhibitors of Bacterial Quorum Sensing 1X01MH078952-01 Screening 24085 64 Completed
52 700 Dose Response Assay for Inhibitors of Bacterial Quorum Sensing 1X01MH078952-01 Confirmatory 94 19 Completed
53 1014 Inhibitors of Bacterial Quorum Sensing Structure Activity Relationship (SAR) Analysis: Primary HTS Assay 1X01MH078952-01 Screening 240 26 Completed
54 1015 Inhibitors of Bacterial Quorum Sensing Structure Activity Relationship (SAR) Analysis: Dose Response Assay 1X01MH078952-01 Confirmatory 32 32 Completed
55 1206 Inhibitors of Bacterial Quorum Sensing: Summary 1X01MH078952-01 Summary 45 45 Completed
56 950 Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2 1X01MH079850-01 Screening 134474 104 In progress
57 951 Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B 1X01MH079850-01 Screening 134474 133 In progress
58 952 Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W 1X01MH079850-01 Screening 134474 28 In progress
59 1007 Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL 1X01MH079850-01 Screening 134474 69 In progress
60 1008 Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 1X01MH079850-01 Screening 134474 179 In progress
61 1009 Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Mcl-1 1X01MH079850-01 Screening 134474 154 In progress

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